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| BRIEF COMMUNICATION |
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| Year : 2022 | Volume
: 3
| Issue : 3 | Page : 92-93 |
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Behçet's disease presenting as cerebral venous thrombosis
Pratibha Prasad1, Prem Shanker Verma2
1 Department of Neurologydr, Dr. S. N. Medical College, Rajasthan University of Health Science, Jodhpur, Rajasthan, India
2 Department of Neurosurgery, I.M.S. B.H.U, Varanasi, Uttar Pradesh, India
| Date of Submission | 04-Dec-2021 |
| Date of Decision | 05-Feb-2022 |
| Date of Acceptance | 05-Feb-2022 |
| Date of Web Publication | 03-Nov-2022 |
Correspondence Address:
Pratibha Prasad
Department of Neurologydr, S.N. Medical College, Rajasthan University of Health Science, Jodhpur, Rajasthan
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jascp.jascp_29_21
How to cite this article:
Prasad P, Verma PS. Behçet's disease presenting as cerebral venous thrombosis. J Appl Sci Clin Pract 2022;3:92-3 |
The occurrence of cerebral venous thrombosis (CVT) as a presenting symptom of Behcet's disease (BD) is quite uncommon.[1] Few cases regarding the first presentation of BD with CVT are reported.[2],[3],[4],[5] However, hardly any case in the Indian perspective. Therefore, we report CVT as the initial presentation of Behçet's disease in a 32-year-old immunocompetent Indian male. He presented with severe headache and vomiting with gradual progressive painless loss of vision in both eyes (right > left) for 1½ months. History revealed recurrent oral and genital ulcers in the last 7 months. Neurological examination revealed bilateral papilledema and right sixth cranial nerve palsy. Ophthalmoscopy revealed panuveitis with papilledema in the right eye [Figure 1] more than the left eye [Figure 2]. Magnetic resonance venography showed right transverse sinus and superior sagittal sinus thrombosis [Figure 3]. Thrombophilia screening showed positivity in HLAB51. Pathergy test was positive. A diagnosis of BD was made. The patient was treated with anti-coagulant therapy, immunosuppressive drug, and acetazolamide and was in follow-up for 1 year with no recurrent symptoms. Thus, there is a need to increase the awareness of neuro BD whenever headache due to CVT is associated with oral and genital ulcers. | Figure 1: Fundoscopy showing panuveitis with papilledema in the right eye
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 | Figure 2: Fundoscopy showing panuveitis with papilledema in the left eye
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 | Figure 3: MRV showing right transverse sinus and superior sagittal sinus thrombosis
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Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Aguiar de Sousa D, Mestre T, Ferro JM. Cerebral venous thrombosis in Behçet's disease: A systematic review. J Neurol 2011;258:719-27.  |
| 2. | Ascaso FJ, Rodriguez A, Cristóbal JA. Cranial hypertension as first manifestation of Behçet's disease: A case report. Doc Ophthalmol 2002;105:291-9. |
| 3. | Chaloupka K, Baglivo E, Hofer M, Chizzolini C, Delavelle J, Rossillion B, et al. Cerebral sinus thrombosis in Behçet disease: Case report and review of the literature. Klin Monbl Augenheilkd 2003;220:186-8. |
| 4. | Rahil AI, Errayes M, Salem KM. Cerebral venous thrombosis as the initial presentation of Behcet's disease. Chang Gung Med J 2009;32:220-3. |
| 5. | Can E, Kara B, Somer A, Keser M, Salman N, Yalçin I. Neuro-Behçet disease presenting as secondary pseudotumor syndrome: Case report. Eur J Paediatr Neurol 2006;10:97-9. |
[Figure 1], [Figure 2], [Figure 3]
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