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BRIEF COMMUNICATION
Year : 2022  |  Volume : 3  |  Issue : 3  |  Page : 92-93

Behçet's disease presenting as cerebral venous thrombosis


1 Department of Neurologydr, Dr. S. N. Medical College, Rajasthan University of Health Science, Jodhpur, Rajasthan, India
2 Department of Neurosurgery, I.M.S. B.H.U, Varanasi, Uttar Pradesh, India

Date of Submission04-Dec-2021
Date of Decision05-Feb-2022
Date of Acceptance05-Feb-2022
Date of Web Publication03-Nov-2022

Correspondence Address:
Pratibha Prasad
Department of Neurologydr, S.N. Medical College, Rajasthan University of Health Science, Jodhpur, Rajasthan
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jascp.jascp_29_21

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How to cite this article:
Prasad P, Verma PS. Behçet's disease presenting as cerebral venous thrombosis. J Appl Sci Clin Pract 2022;3:92-3

How to cite this URL:
Prasad P, Verma PS. Behçet's disease presenting as cerebral venous thrombosis. J Appl Sci Clin Pract [serial online] 2022 [cited 2022 Dec 6];3:92-3. Available from: http://www.jascp.org/text.asp?2022/3/3/92/360445



The occurrence of cerebral venous thrombosis (CVT) as a presenting symptom of Behcet's disease (BD) is quite uncommon.[1] Few cases regarding the first presentation of BD with CVT are reported.[2],[3],[4],[5] However, hardly any case in the Indian perspective. Therefore, we report CVT as the initial presentation of Behçet's disease in a 32-year-old immunocompetent Indian male. He presented with severe headache and vomiting with gradual progressive painless loss of vision in both eyes (right > left) for 1½ months. History revealed recurrent oral and genital ulcers in the last 7 months. Neurological examination revealed bilateral papilledema and right sixth cranial nerve palsy. Ophthalmoscopy revealed panuveitis with papilledema in the right eye [Figure 1] more than the left eye [Figure 2]. Magnetic resonance venography showed right transverse sinus and superior sagittal sinus thrombosis [Figure 3]. Thrombophilia screening showed positivity in HLAB51. Pathergy test was positive. A diagnosis of BD was made. The patient was treated with anti-coagulant therapy, immunosuppressive drug, and acetazolamide and was in follow-up for 1 year with no recurrent symptoms. Thus, there is a need to increase the awareness of neuro BD whenever headache due to CVT is associated with oral and genital ulcers.
Figure 1: Fundoscopy showing panuveitis with papilledema in the right eye

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Figure 2: Fundoscopy showing panuveitis with papilledema in the left eye

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Figure 3: MRV showing right transverse sinus and superior sagittal sinus thrombosis

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Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Aguiar de Sousa D, Mestre T, Ferro JM. Cerebral venous thrombosis in Behçet's disease: A systematic review. J Neurol 2011;258:719-27.  Back to cited text no. 1
    
2.
Ascaso FJ, Rodriguez A, Cristóbal JA. Cranial hypertension as first manifestation of Behçet's disease: A case report. Doc Ophthalmol 2002;105:291-9.  Back to cited text no. 2
    
3.
Chaloupka K, Baglivo E, Hofer M, Chizzolini C, Delavelle J, Rossillion B, et al. Cerebral sinus thrombosis in Behçet disease: Case report and review of the literature. Klin Monbl Augenheilkd 2003;220:186-8.  Back to cited text no. 3
    
4.
Rahil AI, Errayes M, Salem KM. Cerebral venous thrombosis as the initial presentation of Behcet's disease. Chang Gung Med J 2009;32:220-3.  Back to cited text no. 4
    
5.
Can E, Kara B, Somer A, Keser M, Salman N, Yalçin I. Neuro-Behçet disease presenting as secondary pseudotumor syndrome: Case report. Eur J Paediatr Neurol 2006;10:97-9.  Back to cited text no. 5
    


    Figures

  [Figure 1], [Figure 2], [Figure 3]



 

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